• PCH202 INTRODUCTION TO PHARMACEUTICAL CHEMISTRY

    3 Credit

    a. Physical Chemistry: Principles of thermodynamics, chemical and ionic equilibra. Chemical kinetics. Phase equilibrum study of multi-components systems and applications in partition and absorption chromtography.

    b. Radiopharmaceuticals, radioisotopes, types and sources of radio-active decay particules and thgeir measurements. Biological effects of radiation; pharmaceutical application of radioisotopes.

    c. At least 10 practicals to illustrate the concept outlined above.

  • Mechanism of Organic Reactions: There are thousands of organic named reactions, yet they all occur by mechanisms that are a combination of relatively few pathways of electron flow. All the electron sources and sinks can react by at least one of these pathways or a combination of them. We will learn what sort of functionality is required for each pathway and also notice the limitations on each pathway. Each of these pathways has four charge types since the source and or the sink can be charged or neutral:
    (1.) Nu with E, (2.) Nu- with E, (3.) Nu with E+, and (4.) Nu- with E+.

  • PCH303 PHARMACEUTICAL ANALYSIS I 3 Credits

    Pre-requisite: PCH 202

    a. Basic methods of analysis including aqueous and non-aqueous acid-base titration, redox and complexometric titration, gravimetric analysis and limit tests.

    b. At least 10 practicals to illustrate concepts outlined above.

  • [PCH 402 - Pharmaceutical Analysis II] This is a 3-credit course designed to introduce Undergraduate students in the B. Pharm programme to instrumental methods in Pharmaceutical Analysis involving identification, structure elucidation and quantitation of drugs and chemicals using spectroscopic and chromatographic methods. The methods include Ultraviolet/Visible Spectrophotometry, Atomic Absorption/Flame Emission spectrometry, Fluorimetry, Infrared spectroscopy, Nuclear Magnetic Resonance (NMR) spectroscopy, Mass Spectrometry, Structure Elucidation by application of spectroscopic data, Chromatography and Hyphenated techniques. At least 10 practical sessions are to be carried out to illustrate the concepts taught [Note: This course was originally offered in 400 Level 2nd Semester but is now offered in 500 Level 1st Semester because of the SIWES programme taken at the 400 Level]
  • PCH 502 ANALYTICAL ASPECTS OF DRUG QUALITY 2 Credits

    a. Photochemistry: General principles; characteristics of photochemical reactions and applications in pharmacy.

    b. Drug quality control assurance systems: introduction to the problems of drug quality control. Official methods of drug analysis. Analytical methods used by the manufactures, importance of standards, uses to storage.

    c. Monographs and specifications for drugs and drugs products. Equivalence and bio-equivalence of drug products.

    d. Applications of chemical physico-chemical and bio-pharmaceutical analytical methods in identification and quantitations of drugs.

    e. At least 10 practicals to illustrate the concepts outlined above.